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A: Definitions, Explanations, Translations

 Subject
Subject Source: Local sources
Scope Note: A-Codes relate to the interview subject (e.g. Values, Faith, Education)

Found in 5 Collections and/or Records:

Chapter 01: A New Idea and A Controversy: Transfusing Platelets in Leukemia Patients, 2011-10-05

 Sub-Fonds
Identifier: MCHV-Freireich
Overview Dr. Freireich begins this segment by explaining the origin of his first name, “J”. Next, he describes how he worked with pediatric patients in the fifties, noting that he would see blood sprays on the walls of childrens’ hospital rooms from their hemorrhages. This led to his decision to treat the patients with massive doses of platelets. Dr. Freireich gives detailed accounts of the patients’ physiology, the technical challenges to overcome when giving patients blood from donors (as opposed to a...
Dates: 2011-10-05

Chapter 02: Building the Continuous-Flow Blood Separator, 2011-10-05

 Sub-Fonds
Identifier: MCHV-Freireich
Overview In this segment, Dr. Freireich describes treating infections by transfusing white blood cells. He goes over the technical difficulties of separating white cells from platelets. (He describes his lab at NCI, festooned with 50 feet of tubing.) Here he also specifies why a continuous flow of blood was needed: using the analogy of an artificial kidney, he explains that leukemia patients required a huge number of either platelets or white blood cells, so the aim was to process a donor’s entire blood...
Dates: 2011-10-05

Chapter 13: Leukemia as a Key to Understanding Cancer, 2011-10-05

 Sub-Fonds
Identifier: MCHV-Freireich
Overview In this segment, Dr. Freireich presents his theory that the ability to control cancer (determining which cancers will metastasize and kill) will come from research in leukemia because leukemia is a systemic cancer and everything discovered about it is immediately transferable to solid tumors. He talks about molecular and genetic advances in understanding cancer. He notes that we don’t need to understand the source of cancer, since will never be eradicate it, we need to understand how cancer...
Dates: 2011-10-05

Chapter 14: The Partnership Between Basic Science and Clinical Research, 2011-10-05

 Sub-Fonds
Identifier: MCHV-Freireich
Overview In this segment, Dr. Freireich further clarifies his view of the relationship between clinical and basic research. "I want to spend double the money on basic research. The problem is the translation. If you don’t have the clinical arm, it’s like trying to play the piano with one hand. We need basic sciences to do the rhythm and the clinical scientists to do the melody and then we get music." He talks about some of his collaborations with basic sciences, but also gives examples of how, contrary...
Dates: 2011-10-05